nervous system

Passionflower

Passiflora incarnata

西番莲

Pinyin: Xī Fān Lián

🌿

Plant Family

Passifloraceae

Part Used

Aerial parts (leaves, flowers, stems)

Origin

Southern US, Mexico, Central America

Safety Level

Safe

Overview

Passionflower is a climbing vine with beautiful, intricate purple-white flowers. It was used by Native Americans for various ailments and is now a popular herbal remedy for anxiety and insomnia. The name "passionflower" was given by Spanish missionaries who saw the flower parts as symbols of the Passion of Christ.

Traditional Chinese Medicine Properties

Nature (四气)

cool

Flavors (五味)

bitter

Meridians (归经)

heart, liver, nervous system

Health Benefits

Reduces anxiety symptoms (comparable to some prescription drugs in studies)
Improves sleep quality and reduces insomnia
May help with adjustment disorder with anxiety
Reduces symptoms of opioid withdrawal
May reduce menopausal hot flashes
Antispasmodic - relieves muscle tension
May help with ADHD symptoms in children

Traditional Uses

  • Anxiety and nervousness
  • Insomnia and sleep disorders
  • Nervous stomach and gastrointestinal upset
  • Menopause symptoms (hot flashes, anxiety)
  • Pain relief (mild)
  • Seizures and hysteria (historical)

Active Constituents

The key compounds responsible for this herb's therapeutic effects:

Flavonoids (apigenin, luteolin, quercetin, vitexin, isovitexin)Vitexin and isovitexin - important active compoundsMaltol and ethyl maltolAlkaloids (harman, harmine, harmaline - very small amounts)Cyanogenic glycosides (gynocardin)SterolsAmino acids (GABA)

Usage & Dosage

How to Use

Used as tea, tincture, capsules, tablets, and liquid extracts. Often combined with other calming herbs like valerian, lemon balm, and hops in sleep and anxiety formulas.

Suggested Dosage

Tea: 1-2 tsp dried herb, steeped 10-15 min. Capsules: 300-600mg standardized extract. Tincture: 2-5ml 2-3 times daily. For anxiety: 45 drops of tincture or 400-800mg extract 3 times daily.

Quality & Storage

Harvest Season

Summer, when the plant is in flower. Aerial parts are harvested and dried.

Quality Indicators

Green herb with visible flowers and leaves, mild grassy-bitter taste. Standardized extracts may list vitexin or flavonoid content.

Storage

Store dried herb in airtight container in cool, dark place. Shelf life: 1-2 years.

Safety Information

Contraindications

Pregnancy (uterine stimulant - may cause contractions)BreastfeedingSurgery (discontinue 2 weeks before - sedative effects)Children under 6 (insufficient data)Liver disease (very rare reports of liver toxicity)

Possible Side Effects

  • Generally safe when used as directed
  • Drowsiness and dizziness
  • Nausea and digestive upset
  • Rapid heart rate (in sensitive individuals)
  • Confusion (in high doses)
  • Very rare: liver toxicity (long-term high doses - unconfirmed)
  • May cause mental impairment - do not drive or operate machinery

Drug Interactions

  • Sedatives and CNS depressants (alcohol, benzodiazepines, barbiturates)
  • Antidepressants (SSRIs, MAOIs - serotonin syndrome risk, though low)
  • Blood thinners (warfarin)
  • Anticonvulsants
  • HIV medications
  • Anesthesia (discontinue before surgery)

Note: Always consult with a qualified healthcare practitioner before starting any herbal supplement, especially if you are pregnant, nursing, have medical conditions, or take medications.

References & Research

Information on this page is based on traditional herbal knowledge and modern scientific research. For a comprehensive list of references, please refer to our full citations page.

ℹ️ Disclaimer

This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. The FDA has not evaluated these statements. Always consult a qualified healthcare provider before using herbal supplements.